ParkinsonCanadaV1, Main, Exploration, bibRecord, 001C11

Improving adeno‐associated vector yield in high density insect cell cultures

Identifieur interne : 001C11 ( Main/Exploration ); précédent : 001C10; suivant : 001C12

Improving adeno‐associated vector yield in high density insect cell cultures

Auteurs : Jimmy A. Mena [Canada] ; Marc G. Aucoin [Canada] ; Johnny Montes [Canada] ; Parminder S. Chahal [Canada] ; Amine A. Kamen [Canada]

Source :

The Journal of Gene Medicine [ 1099-498X ] ; 2010-02.

RBID : ISTEX:614EDD31880A213859FC44B9CBF5D3B44F8A39C6

English descriptors

KwdEn :
- adeno‐associated virus (AAV) vectors, baculovirus, fed‐batch, gene therapy, high cell density, insect cells.

Abstract

Recombinant adeno‐associated virus (rAAV) are the most promising vectors for gene therapy. However, large‐scale rAAV production remains a challenge for the translation of rAAV‐based therapeutic strategies to the clinic. The baculovirus expression vector system (BEVS) has been engineered to produce high rAAV titers in serum‐free suspension cultures of insect cells.

Url:

https://api-v5.istex.fr/document/614EDD31880A213859FC44B9CBF5D3B44F8A39C6/fulltext/pdf

DOI: 10.1002/jgm.1420

Affiliations:

Canada

Links toward previous steps (curation, corpus...)

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to stream Main, to step Curation: 001C11

Le document en format XML

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	La maladie de Parkinson au Canada (serveur d'exploration)
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La maladie de Parkinson au Canada (serveur d'exploration)

Improving adeno‐associated vector yield in high density insect cell cultures

Improving adeno‐associated vector yield in high density insect cell cultures

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri